Blog
Short articles on topics that often arise in clinical practice—written as supportive information, not product promotion.
This blog discusses topics that frequently come up in clinical practice, in short articles. The pieces are not prepared as product promotion. Scientific aspects of current product areas are examined to offer supportive information on how they may be useful in clinical practice.
Telomere attrition: chromosome ends and ageing
Telomere attrition weakens the protection of chromosome ends. Management relies on prevention, awareness of measurement limits and functional monitoring.
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Altered intercellular communication: inflammation, signalling, and ageing
When intercellular communication fails, the inflammatory and signalling environment shifts. Management relies on lifestyle measures, vaccination and functional monitoring.
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Senescent cells: SASP, accumulation, and ageing
Accumulating senescent cells drive inflammation through the SASP. Management relies on exercise, metabolic balance and functional monitoring.
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Deregulated nutrient sensing: metabolism and ageing
Deregulated nutrient sensing disturbs the mTOR–AMPK balance. Management relies on nutrition, physical activity and indicated metabolic therapy.
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Epigenetic alterations: gene expression and ageing
Epigenetic drift disrupts the timing of gene expression while the DNA sequence is unchanged. Management relies on prevention, functional monitoring and cautious measurement.
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Loss of proteostasis: protein maintenance and ageing
Loss of proteostasis occurs when proteins can no longer be correctly folded and cleared. Management relies on exercise, indicated treatment and functional monitoring.
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Mitochondrial dysfunction: energy, mitophagy, and ageing
Mitochondrial dysfunction disrupts the balance of ATP production, ROS and mitophagy. Management relies on exercise, metabolic balance and functional monitoring.
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Stem cell exhaustion: the regenerative pool and ageing
Stem cell exhaustion narrows the niche and the regenerative reserve. Management relies on exercise, protection of the niche and functional monitoring.
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Choosing compression pressure (mmHg)
mmHg classes in graduated medical compression: pressure is chosen only after CEAP stage, ABPI and patient adherence are assessed together. B2B order and stock notes.
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Genomic instability: DNA maintenance and ageing
Genomic instability arises when the balance between DNA damage and repair breaks down. Management relies on prevention, appropriate clinical follow-up and functional monitoring.
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